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these results also show that high-dose allopurinol prolongs exercise in stable angina pectoris on the basis of our results, allopurinol is a useful anti-ischaemic treatment option in patients with angina that has the advantage of being inexpensive, well tolerated and safe in the long term.
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in view of the cost effectiveness or efficacy of other drug treatments for similar indications, not prescribing allopurinol to hla-b 58 01 positive patients is likely to be prudent, despite the low estimated positive predictive value 2 of the test.
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